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Cardiovascular agent
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Adalat CC is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
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Initially, 30 mg to 60 mg once daily. Adjust dosage at 7- to 14-day intervals according to patient tolerance and response. Maximum dosage is 120 mg daily.
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Category C
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Most common: leg swelling, headache, flushing, heat sensation, dizziness, fatigue, and constipation.
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Pregnancy Risk Categories defined:
A: Studies in pregnant women failed to show a risk to the fetus in the first
trimester - with no evidence of risk in the later trimesters.
B: Animals studies indicate no adverse effect to the fetus, but there are no adequate,
clinical studies in pregnant women.
C: Animal studies have shown an adverse effect on the fetus, but there are no adequate,
clinical studies in humans. Despite potential risks, the drug may be useful in pregnant
women.
D: There is evidence of risk to the human fetus, but the potential benefits of use in
pregnant women may be acceptable, despite potential risks.
X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports
indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any
potential benefit from using the drug in pregnant women, regardless of trimester.
NR: Not rated (i.e., no information available at this time as to the potential
risks or benefits).
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