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Alupent (Metaproterenol sulfate)
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Respiratory agent
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Bronchodilator
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Alupent is indicated as a bronchodilator for bronchial Asthma and for reversible bronchospasm that may occur in association with Bronchitis and emphysema.
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Adults: 20 mg 3 to 4 times daily. Not recommended for children less than 6 years of age. Ages 6 to 9 years and less than 60 pounds: 10 mg 3 to 4 times daily. Ages: 9 to 12 years and more than 60 pounds: 20 mg 3 to 4 times daily. Syrup: Children 6 to 9 years or less than 60 pounds: 5mL 3 to 4 times daily. Ages 9 and older or more than 60 pounds: 10 mL 3 to 4 times daily. Adults: 10 mL 3 to 4 times daily before or after meal.
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Category C
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Pregnancy Risk Categories defined:
A: Studies in pregnant women failed to show a risk to the fetus in the first
trimester - with no evidence of risk in the later trimesters.
B: Animals studies indicate no adverse effect to the fetus, but there are no adequate,
clinical studies in pregnant women.
C: Animal studies have shown an adverse effect on the fetus, but there are no adequate,
clinical studies in humans. Despite potential risks, the drug may be useful in pregnant
women.
D: There is evidence of risk to the human fetus, but the potential benefits of use in
pregnant women may be acceptable, despite potential risks.
X: Studies in animals or humans show fetal abnormalities, or adverse reaction reports
indicate evidence of fetal risk. Warning: the risks involved clearly outweigh any
potential benefit from using the drug in pregnant women, regardless of trimester.
NR: Not rated (i.e., no information available at this time as to the potential
risks or benefits).
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