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Welcome, eCureMe.com medical contents search May 9, 2013
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Cortisol


  • A group of hormone called glucocorticoids

  • Plasma

  • Adult
    1. 8 a.m-10 a.m: 5-23 µg/dl
    2. 4 p.m-6 p.m: 3-13 µg/dl

  • To diagnose Cushing's Syndrome, Cushing's disease, and primary and secondary adrenal insufficiency
  • To distinguish between primary and secondary adrenal insufficiency

  • Stress
  • Acute illness
  • Surgery
  • Trauma
  • Pregnancy
  • Anxiety
  • Exogenous estrogen
  • Starvation
  • Anorexia nervosa
  • Alcoholism
  • Renal failure

  • Addison's disease
  • Hypophysectomy
  • Postpartum pituitary necrosis
  • Pituitary destruction

  • Noncompliance with dietary or activity restrictions
    1. With RIA: Androgen, Estrogen, Phenytoin, Hepatic dysfunction, renal failure
    2. With competitive protein binding assay: Prednisolone, 6-alpha-methylprednisolone
    3. With fluorometric assays: Jaundice, renal failure, medications
    4. With high-performance liquid chromatography: Prednisone, prednisolone










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