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Ligneous Thyroiditis

more about Ligneous Thyroiditis


Riedel's thyroiditis, woody thyroiditis or invasive fibrous thyroiditis

  • This form of Thyroiditis is usually found in elderly and middle-aged women. It is quite rare. In this disease, the patient has a very hard thyroid gland, as well as symptoms caused by pressure put on other structures in the neck. Treatment is with a medicine called Tamoxifen.

  • The thyroid gland is enlarged, hard, and does not move very freely.
  • The thyroid gland becomes very hard because of all the fibrous tissue that has invaded it.
  • The patient often has symptoms due to pressure on other structures in the neck. These symptoms may include difficulty swallowing and breathing, pain in the neck area, or hoarseness.
  • The patient usually has symptoms of Hypothyroidism.

  • Riedel's Thyroiditis is caused by fibrous tissue invading the thyroid gland. It is not known why this happens.
  • However, many people with this disease have other related diseases, such as retroperitoneal fibrosis, fibrosing mediastinitis, biliary tract sclerosis, or sclerosing Cervicitis.

  • The symptoms and examination help make the diagnosis.
  • Usually, the T4 and T3 resin uptake (these are tests of the thyroid gland) are often low.
  • A Nuclear scan of the thyroid gland usually shows low uptake.
  • The TSH (thyroid stimulating hormone) level is usually increased.
  • Sometimes a biopsy may be needed to confirm the diagnosis.

  • Treatment is with Tamoxifen. Tamoxifen is often used to treat women with Breast Cancer. However, it also works quite well for people with Riedel's Thyroiditis.
  • Tamoxifen leads to either partial or complete remission in most people within 3-6 months.
  • Treatment, however, usually needs to be continued for years.
  • Also, some people are treated with steroids in order to try to reduce some of the pain and swelling associated with this condition.
  • Surgery is done only if absolutely necessary. Surgery is usually very difficult and often not very successful.




more about Ligneous Thyroiditis


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