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Preimplantion Genetic Diagnosis
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Preimplantion Genetic Diagnosis
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Also known as
PGD
Procedure
This test screens for abnormal genes and numerical or structural problems with the chromosomes, using molecular biological techniques and microsurgical techniques to determine if there are any genetic abnormalities with the zygote about to be transferred.
Administration
* After investigating the parents' genetic diseases, a probe that can analyze genes and chromosomes is prepared.
* An egg is collected from the woman via the same technique as the test-tube procedure.
* After collecting the husband's sperm and fertilizing it externally, the zygote is cultivated for 2 or 3 days until cells begin to split.
* The cells making up each zygote are separated using a microinstrument.
* The separated cells are checked for genetic abnormalities by using genetic analyzing techniques such as polymerization chain reaction and FISH (fluorescent in situ hybridization).
* Only selected normal zygotes are transferred to the woman's uterus.
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