• This is a disease characterized by very large blisterlike lesions (bullae) that usually occur in the elderly. It tends to come and go, then disappear after 5 or 6 years.

• Large blistering lesions in flexural areas, i.e., the creases of the body
• Itching
• Gum or mouth sores
• Rash may be present
• Skin ulcers may form

• Autoimmune (the body's immune system mistakenly causes a reaction)

1. Methotrexate (an anticancer drug)
2. Azathioprine

• Pemphigus
• Bullous impetigo

• Note

- It is important to distinguish Bullous Pemphigoid from Pemphigus. Pemphigus is a much more serious disease. Bullous Pemphigoid occurs exclusively in the creases of the body. If there is blistering outside this area, Pemphigus is the more likely cause.