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Berger's disease, focal glomerulonephritis
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- This is a kidney disorder in which IgA antibodies deposit in the internal kidney structures and cause inflammation.
- It is more common in boys than girls.
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Family history of IgA
nephropathy or Henoch-Schonlein purpura
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- Bloody urine
- Dark, brown, or rust-colored urine
- High blood pressure
- Edema
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- Based on symptoms and physical examination
- Urine tests show blood, red cell casts, protein and fat in the urine.
- Kidney biopsy shows deposits of IgA antibodies.
- Immunoelectrophoresis of urine shows antibodies to IgA.
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- Antihypertensive medications
- Diuretics
- Low-to-moderate protein diet in some cases
- Immunosuppressive therapy for progressive IgA nephropathy
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- Renal failure
- High blood pressure
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- It progresses in 30% of patients.
- Poor prognosis is associated with:
- High blood pressure
- Diminished kidney function
- Histologic evidence of diffuse glomerulonephritis with crescents and scarring
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